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Structure of 24195-07-1
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2-(Methoxycarbonyl)nicotinic acid is a bench-stable, moisture-tolerant heterocyclic carboxylic acid featuring a methoxycarbonyl group at the 2-position of the pyridine ring. This configuration enhances electrophilicity at the carbonyl carbon, enabling direct coupling reactions in peptide and macrocycle synthesis. The para-carboxylic acid moiety provides a versatile anchor for conjugation, facilitating integration into bioconjugates and pharmaceutical intermediates under standard conditions.
2-(Methoxycarbonyl)nicotinic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling efficient access to pyridine-based scaffolds. Its dual functionality—carboxylic acid and ester groups—facilitates selective derivatization, including amidation, reduction, and palladium-catalyzed coupling reactions. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: