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CS-W001157 4
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6-Amino-1-methylpyrimidine-2,4(1H,3H)-dione

  • CAS No. 2434-53-9

  • Cat. No. CS-W016441
  • Molecule weight141.13
  • Purity≥98%
  • MDL No.MFCD00075366

*For research and further manufacturing use only, not for direct human use.

6-Amino-1-methylpyrimidine-2,4(1H,3H)-dione|CS-W016441

Structure of 2434-53-9

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General Information

  • CAS No. 2434-53-9
  • Cat. No. CS-W016441
  • Purity ≥98%
  • MDL No. MFCD00075366
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇N₃O₂
  • Molecular Weight 141.13
  • Synonym(s) 6-Amino-1-methyluracil
  • SMILES CN1C(=O)NC(=O)C=C1N

Description

6-Amino-1-methyluracil is an amino derivative of uracil and its standard molar enthalpy of combustion has been evaluated. Host-guest complexation of 6-amino-1-methyluracil with tetrapropoxycalix[4]arene has been reported.6-Amino-1-methyluracil may be used in the preparation of 1,1-di methyl-1H-spiro[pyrimido[4,5-b]quinoline-5,5-pyrrolo[2,3-d]pyrimidine]-2,2,4,4,6(1H,3H,3H,7H,1H)-pentaone, via reaction with isatin in the presence of catalytic p-toluene sulfonic acid.

Synthesis

  • Route1
    • null|null
      105-56-6
    • In-stock
      1-Methylurea|CS-W016687
      598-50-5
    • ~94%
    • In-stock
      6-Amino-1-methylpyrimidine-2,4(1H,3H)-dione|CS-W016441
      2434-53-9

    References

    • Sun, Hongmao; Zhi, Chengxin; Wright, George E.; Ubiali, Daniela; Pregnolato, Massimo; Verri, Annalisa; Focher, Federico; Spadari, Silvio Journal of Medicinal Chemistry, 1999 , vol. 42, # 13 p. 2344 - 2350
  • Route2
    • null|null
      372-09-8
    • In-stock
      1-Methylurea|CS-W016687
      598-50-5
    • ~69%
    • In-stock
      6-Amino-1-methylpyrimidine-2,4(1H,3H)-dione|CS-W016441
      2434-53-9

    References

    • Devi, Ipsita; Bhuyan, Pulak J. Tetrahedron Letters, 2005 , vol. 46, # 34 p. 5727 - 5729
  • Route3
    • 2-Cyano-N-(methylcarbamoyl)acetamide|CS-0365281
      6972-77-6
    • ~88%
    • In-stock
      6-Amino-1-methylpyrimidine-2,4(1H,3H)-dione|CS-W016441
      2434-53-9

    References

    • Fuelle, Friederike; Mueller, Christa E. Heterocycles, 2000 , vol. 53, # 2 p. 347 - 351

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   80.88
  • LogP   -1.3442
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   0

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