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Structure of 2436-85-3
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N,N-Dimethylnaphthalen-2-amine is a bench-stable, electron-rich amine featuring a para-dimethylamino group on a naphthalene core. This configuration enhances its utility in transition-metal-catalyzed cross-coupling reactions and as a ligand in palladium-mediated transformations. The compound exhibits good solubility in organic solvents and maintains reactivity under standard conditions.
N,N-Dimethylnaphthalen-2-amine serves as a robust electron-rich aryl amine scaffold, enabling efficient palladium-catalyzed cross-coupling reactions. Its dimethylamino group enhances nucleophilicity and stabilizes intermediates in Buchwald–Hartwig amination protocols. The compound exhibits excellent bench stability, facilitates straightforward purification via silica gel chromatography, and functions as a versatile building block for functionalized heterocycles and advanced pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: