Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Bromo-2-nitrothiophene

  • CAS No. 24430-27-1

  • Cat. No. CS-W021858
  • Purity≥97%
  • MDL No.MFCD04971288

*For research and further manufacturing use only, not for direct human use.

3-Bromo-2-nitrothiophene|CS-W021858

Structure of 24430-27-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 24430-27-1
  • Cat. No. CS-W021858
  • Purity ≥97%
  • MDL No. MFCD04971288
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₂BrNO₂S
  • Molecular Weight 208.03
  • Synonym(s) 2-Nitro-3-bromothiophene
  • SMILES O=[N+](C1=C(Br)C=CS1)[O-]

Description

3-Bromo-2-nitrothiophene features a thiophene core functionalized with bromine at the 3-position and a nitro group at the 2-position, delivering high reactivity in cross-coupling and electrophilic substitution reactions. The electron-deficient nature of the ring enhances its utility in transition-metal-catalyzed transformations. This bench-stable compound serves as a key intermediate in the synthesis of bioactive heterocycles and advanced materials.

Application

3-Bromo-2-nitrothiophene serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo group and electron-withdrawing nitro functionality. The molecule exhibits good bench stability and facilitates sequential functionalization, with the nitro group amenable to reduction and subsequent derivatization. Its orthogonal reactivity profile supports efficient access to substituted thiophene scaffolds relevant to medicinal chemistry and materials science.

Synthesis

  • Route1

    References

    • Justus Liebigs Annalen der Chemie, , vol. 512, p. 136,156 Nippon Kagaku Zasshi, , vol. 78, p. 950,962 Chem. Zentralbl., , vol. 129, p. 13204

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   43.14
  • LogP   2.4188
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Bromo-2-nitrothiophene sigma3-Bromo-2-nitrothiophene manufacturer3-Bromo-2-nitrothiophene price3-Bromo-2-nitrothiophene structure3-Bromo-2-nitrothiophene SDSbuy 3-Bromo-2-nitrothiophene3-Bromo-2-nitrothiophene supplier3-Bromo-2-nitrothiophene uses3-Bromo-2-nitrothiophene molecular weightprice of 3-Bromo-2-nitrothiophene3-Bromo-2-nitrothiophene chemical name formula of 3-Bromo-2-nitrothiophene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label