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Structure of 54396-44-0
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2-Methyl-3-(trifluoromethyl)aniline belongs to the trifluoromethylbenzene series.2-Methyl-3-(trifluoromethyl)aniline may be used in chemical synthesis.
2-Methyl-3-(trifluoromethyl)aniline serves as a valuable building block in medicinal chemistry, enabling the synthesis of trifluoromethylated aromatic scaffolds. Its electron-withdrawing trifluoromethyl group enhances metabolic stability and modulates lipophilicity, while the ortho-methyl substituent supports directed metallation and regioselective functionalization. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, facilitating efficient access to complex heterocyclic systems and API intermediates.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅱ
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Hazard Statements : H314-H318-H330
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Precautionary Statements : P260-P264-P271-P280-P284-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P320-P363-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: