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Structure of 24430-27-1
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3-Bromo-2-nitrothiophene features a thiophene core functionalized with bromine at the 3-position and a nitro group at the 2-position, delivering high reactivity in cross-coupling and electrophilic substitution reactions. The electron-deficient nature of the ring enhances its utility in transition-metal-catalyzed transformations. This bench-stable compound serves as a key intermediate in the synthesis of bioactive heterocycles and advanced materials.
3-Bromo-2-nitrothiophene serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo group and electron-withdrawing nitro functionality. The molecule exhibits good bench stability and facilitates sequential functionalization, with the nitro group amenable to reduction and subsequent derivatization. Its orthogonal reactivity profile supports efficient access to substituted thiophene scaffolds relevant to medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: