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CS-W001157 4
Total: USD 88.00

5'-Methylthioadenosine

  • CAS No. 2457-80-9

  • Cat. No. CS-0012983
  • Molecule weight297.33
  • Purity≥96%
  • MDL No.MFCD00010533

*For research and further manufacturing use only, not for direct human use.

5'-Methylthioadenosine|CS-0012983

Structure of 2457-80-9

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General Information

  • CAS No. 2457-80-9
  • Cat. No. CS-0012983
  • Purity ≥96%
  • MDL No. MFCD00010533
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₅N₅O₃S
  • Molecular Weight 297.33
  • Synonym(s) 5'-(Methylthio)-5'-deoxyadenosine; 5'-Deoxy-5'-(methylthio)adenosine; 5'-S-Methyl-5'-thioadenosine
  • SMILES NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CSC)O3

Description

5′-Deoxy-5′-methylthioadenosine (CAS 2457-80-9) inhibits methionine salvage pathway enzymes by covalently modifying cysteine residues, disrupting purine metabolism and inducing cellular stress in cancer cell lines.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   119.31
  • LogP   -0.6093
  • H_Acceptors   9
  • H_Donors   3
  • Rotatable_Bonds   3

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