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Structure of 609-15-4
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Ethyl 2-chloroacetoacetate is a versatile β-keto ester derivative featuring a chlorine-substituted acetyl moiety. This electrophilic handle enables efficient alkylation and condensation reactions in synthetic organic chemistry. The molecule exhibits enhanced reactivity compared to non-halogenated analogs, facilitating rapid access to substituted heterocycles and carbonyl-containing frameworks under mild conditions.
Ethyl 2-chloroacetoacetate serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of substituted pyridines, quinolines, and other heterocyclic scaffolds via condensation and cyclization protocols. Its α-halo ketone functionality facilitates nucleophilic substitution and enolate-mediated transformations with high regiocontrol. The compound exhibits good bench stability and is readily purified by distillation or column chromatography, making it well-suited for multi-step synthesis and process-scale applications.
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GHS No : GHS05,GHS07,GHS09
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Signal Word : Danger
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UN#: 2920
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Class : 8(3)
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Packing Group : Ⅱ
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Hazard Statements : H227-H302-H314-H318-H335-H400
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Precautionary Statements : P210-P261-P264-P270-P271-P273-P280-P301+P330+P331-P303+P361+P353-P363-P370+P378-P391-P403+P233-P403+P235-P405-P501
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Lot numbers can be found on the outside label of a product: