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Structure of 246023-54-1
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This boronate moiety features a methoxy-substituted aryl core with methyl groups at the 2- and 5-positions, enhancing solubility and stability. The para-methoxy group directs coupling reactions with high regioselectivity, while the sterically shielded boronic acid facilitates reliable Suzuki-Miyaura cross-couplings under standard conditions.
(4-Methoxy-2,5-dimethylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its ortho-dimethyl substitution enhances stability and reduces protodeboronation, while the para-methoxy group improves solubility and modulates electronic properties. The compound exhibits excellent bench stability, facilitates straightforward purification, and is compatible with a broad range of functional groups, making it well-suited for the synthesis of complex pharmaceutical intermediates and functionalized aromatic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: