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Structure of 247564-64-3
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5,6,7-Trifluoro-1H-indole features a fluorinated indole core with enhanced electron deficiency, enabling efficient coupling in cross-coupling reactions. The trifluoromethyl substitution pattern imparts improved metabolic stability and lipophilicity, making it valuable for medicinal chemistry applications. This bench-stable, moisture-tolerant heterocycle integrates readily into complex molecular architectures.
5,6,7-Trifluoro-1H-indole serves as a valuable building block for fluorinated heterocycles, enabling direct functionalization at the indole core due to its electron-deficient aromatic system. The trifluorinated scaffold enhances metabolic stability and modulates electronic properties, facilitating incorporation into bioactive molecules. Its bench-stable nature and compatibility with standard coupling reactions make it suitable for medicinal chemistry campaigns and process-scale synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: