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Structure of 24922-02-9
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Carbethoxymethyl cyclopropyl ketone features a strained cyclopropyl ring fused to a ketone bearing a carbethoxy-methyl side chain. This arrangement imparts high reactivity for cycloaddition and nucleophilic functionalization, enabling efficient construction of complex heterocycles under mild conditions. The molecule exhibits excellent stability during storage and compatibility with common organic solvents.
Carbethoxymethyl cyclopropyl ketone serves as a versatile synthon in heterocyclic synthesis, enabling efficient construction of substituted pyrrolidines and γ-lactams via Michael addition or cyclization cascades. Its cyclopropyl moiety imparts conformational rigidity, while the ester and ketone functionalities offer orthogonal reactivity for sequential transformations. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative medicinal chemistry campaigns and scalable process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: