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Structure of 25016-09-5
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1,3-Dimethyl-1H-pyrazole-5-carbaldehyde features a pyrazole core with methyl groups at the 1- and 3-positions, enhancing steric protection and electronic stability. The aldehyde functionality at the 5-position enables direct coupling in C–C bond-forming reactions, including Wittig and Grignard additions. This bench-stable, moisture-tolerant scaffold integrates readily into heterocyclic libraries for medicinal chemistry and materials science applications.
1,3-Dimethyl-1H-pyrazole-5-carbaldehyde serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling efficient access to pyrazole-based scaffolds. Its aldehyde functionality facilitates reductive amination, Grignard additions, and condensation reactions with amines or hydrazines under mild conditions. The dimethyl substitution enhances bench stability and solubility, while the pyrazole core provides structural rigidity and favorable pharmacophore characteristics. Functions effectively in multistep syntheses requiring orthogonal reactivity and clean purification profiles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: