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Structure of 25016-20-0
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1-Methyl-1H-pyrazole-3-carboxylic acid features a pyrazole core with a methyl group at the N1 position and a carboxylic acid at the C3 position, delivering enhanced solubility and metabolic stability. This scaffold integrates readily into bioactive molecules, serving as a key pharmacophore in kinase inhibitors and CNS-targeted therapeutics. The electron-deficient pyrazole ring supports efficient coupling reactions under standard conditions.
1-Methyl-1H-pyrazole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyrazole-based heterocycles prevalent in pharmaceutical scaffolds. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions with amines or alcohols under standard conditions. The molecule exhibits good bench stability, moderate solubility in common organic solvents, and tolerance to a range of functional groups, supporting its use in multi-step syntheses and late-stage diversification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: