1-Cbz-pyrrolidine

Name: 1-Cbz-pyrrolidine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 25070-74-0
Cat. No. CS-0156223
Purity≥97%
MDL No.MFCD18206031

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 25070-74-0

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Description

1-Cbz-pyrrolidine delivers a protected pyrrolidine scaffold with enhanced solubility and stability, enabling efficient incorporation into complex molecular architectures. This bench-stable reagent facilitates amine functionalization under mild conditions, streamlining synthetic workflows in medicinal chemistry and peptide derivatization.

Application

1-Cbz-pyrrolidine serves as a robust, bench-stable nitrogen protecting group for pyrrolidine derivatives, enabling selective functionalization in complex molecule synthesis. Its carbamate functionality facilitates orthogonal deprotection under mild hydrogenolysis conditions and exhibits excellent compatibility with diverse reaction environments. Widely employed in medicinal chemistry and API development, it functions as a key building block for heterocyclic scaffolds and peptide extensions.

General Information

CAS No. 25070-74-0
Cat. No. CS-0156223
Purity ≥97%
MDL No. MFCD18206031
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₁₅NO₂
Molecular Weight 205.25
Synonym(s) 1-benzyloxycarbonylpyrrolidine
SMILES C1=CC=C(C=C1)COC(=O)N2CCCC2

Computational Chemistry Data

TPSA 29.54
LogP 2.419
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 2

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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1-Cbz-pyrrolidine

CAS No. 25070-74-0

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