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Structure of 455-69-6
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Methyl 2-fluoroisonicotinate is a fluorinated pyridine ester featuring a strategically positioned fluoro substituent at the 2-position. This electron-deficient heterocycle enables direct functionalization in cross-coupling reactions and serves as a key building block for bioactive molecules. The methyl ester group offers enhanced stability and facilitates downstream transformations.
Methyl 2-fluoroisonicotinate serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated heterocyclic scaffolds. Its ortho-fluorinated pyridine core exhibits enhanced metabolic stability and modulated electronic properties, facilitating C–H functionalization and Suzuki-Miyaura coupling reactions. The ester group allows for selective transformations, while the molecule demonstrates excellent bench stability and compatibility with standard purification techniques.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H318
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: