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CS-W001157 4
Total: USD 88.00

2-(2,3-Dihydrothieno[3,4-b][1,4]dioxin-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

  • CAS No. 250726-93-3

  • Cat. No. CS-0091159
  • Purity≥98%
  • MDL No.MFCD08060541
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-(2,3-Dihydrothieno[3,4-b][1,4]dioxin-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0091159

Structure of 250726-93-3

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Description

This boronate ester features a rigid, electron-rich dihydrothienodioxin scaffold that enhances stability and reactivity in Suzuki-Miyaura cross-coupling. The tetramethyl-substituted dioxaborolane ring ensures excellent bench stability and moisture tolerance, enabling reliable use under standard conditions.

Application

This boronate ester serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation with aryl and vinyl halides. The dihydrothienodioxin core imparts stability and favorable solubility, while the tetramethyl-substituted dioxaborolane facilitates mild reaction conditions and excellent functional group tolerance. Its bench-stable nature simplifies handling and purification in synthetic workflows involving heterocyclic scaffolds.

General Information

  • CAS No. 250726-93-3
  • Cat. No. CS-0091159
  • Purity ≥98%
  • MDL No. MFCD08060541
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₇BO₄S
  • Molecular Weight 268.14
  • Synonym(s) 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydrothieno[3,4-b][1,4]dioxine
  • SMILES CC1(C)C(C)(C)OB(C2=C3C(OCCO3)=CS2)O1

Computational Chemistry Data

  • TPSA   36.92
  • LogP   1.8185
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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