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Structure of 1025708-31-9
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This boronate-functionalized pyrimidine integrates seamlessly into Suzuki-Miyaura coupling reactions, offering high stability and compatibility with diverse reaction conditions. The carbonitrile group enhances electronic tuning, while the tetramethylboronate moiety enables efficient cross-coupling without requiring preactivation.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2-carbonitrile serves as a versatile boronate building block for palladium-catalyzed cross-coupling reactions. The pyrimidine core with dual electron-withdrawing groups enables efficient coupling with aryl and heteroaryl halides, while the tetramethylboronate moiety offers excellent bench stability, mild reaction conditions, and compatibility with diverse functional groups. This compound facilitates rapid access to substituted pyrimidine scaffolds commonly found in pharmaceutical intermediates and agrochemicals.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: