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Structure of 251300-32-0
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This trifluoromethyl-substituted benzoic acid features a strategically positioned hydroxyl group, enabling direct conjugation in bioconjugation workflows. The electron-withdrawing trifluoromethyl moiety enhances acidity and metabolic stability, while the ortho-hydroxy arrangement facilitates chelation and solid-phase integration.
2-Hydroxy-3-(trifluoromethyl)benzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to bioactive heterocycles. Its ortho-hydroxyl and trifluoromethyl groups provide enhanced solubility, metabolic stability, and favorable electronic effects for downstream functionalization. The molecule exhibits excellent bench stability and facilitates direct coupling reactions, serving as a key intermediate in the construction of pharmacophores requiring polar, electron-deficient aromatic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: