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CS-W001157 4
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(S)-3-Aminopiperidine-2,6-dione hydrochloride

  • CAS No. 25181-50-4

  • Cat. No. CS-0129473
  • Purity≥96%
  • MDL No.MFCD15474943

*For research and further manufacturing use only, not for direct human use.

(S)-3-Aminopiperidine-2,6-dione hydrochloride|CS-0129473

Structure of 25181-50-4

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General Information

  • CAS No. 25181-50-4
  • Cat. No. CS-0129473
  • Purity ≥96%
  • MDL No. MFCD15474943
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉ClN₂O₂
  • Molecular Weight 164.59
  • Synonym(s) (S)-3-aminopiperidine-2,6-dione hydrochloride(WXC01463)
  • SMILES O=C([C@@H](N)CC1)NC1=O.[H]Cl

Description

(S)-3-Aminopiperidine-2,6-dione hydrochloride is a chiral building block featuring a saturated heterocyclic core with strategically positioned amine and carbonyl functionalities. This configuration enables direct incorporation into bioactive molecule scaffolds, particularly in medicinal chemistry campaigns targeting CNS therapeutics. The hydrochloride salt enhances solubility and stability under standard handling conditions.

Application

(S)-3-Aminopiperidine-2,6-dione hydrochloride serves as a key scaffold in medicinal chemistry, enabling the synthesis of diverse heterocyclic compounds through standard amine functionalization and cyclocondensation reactions. Its bench-stable nature, high solubility in aqueous and polar organic solvents, and compatibility with common coupling protocols facilitate efficient incorporation into drug-like molecules. Functions as a versatile building block for pyrrolidine- and piperidine-based pharmacophores.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   72.19
  • LogP   -0.8279
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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