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CS-W001157 4
Total: USD 88.00

Methyl 4-chlorothieno[2,3-c]pyridine-2-carboxylate

  • CAS No. 251996-85-7

  • Cat. No. CS-0061854
  • Purity≥97%
  • MDL No.MFCD08275131

*For research and further manufacturing use only, not for direct human use.

Methyl 4-chlorothieno[2,3-c]pyridine-2-carboxylate|CS-0061854

Structure of 251996-85-7

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General Information

  • CAS No. 251996-85-7
  • Cat. No. CS-0061854
  • Purity ≥97%
  • MDL No. MFCD08275131
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆ClNO₂S
  • Molecular Weight 227.67
  • Synonym(s) None
  • SMILES COC(=O)C1=CC2=C(C=NC=C2S1)Cl

Synthesis

  • Route1

    References

    • AMGEN INC. Patent: WO2009/11871 A2, 2009 ; Location in patent: Page/Page column 130-131 ; WO 2009/011871 A2
  • Route2
    • 3,5-Dichloropyridine Etoricoxib  Impurity|CS-0229442
      2457-47-8
    • ~%
    • Methyl 4-chlorothieno[2,3-c]pyridine-2-carboxylate|CS-0061854
      251996-85-7

    References

    • Stewart; Bhatia; McCarty; Patel; Staeger; Arendsen; Gunawardana; Melcher; Zhu; Boyd; Fry; Cool; Kiflie; Lartey; Marsh; Kempf-Grote; Kilgannon; Wisdom; Meyer; Gallatin; Okasinskit Journal of Medicinal Chemistry, 2001 , vol. 44, # 6 p. 988 - 1002

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   2.7363
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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