Eribulin

Name: Eribulin
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 253128-41-5
Cat. No. CS-2802
Purity≥98%
MDL No.MFCD23160037

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 253128-41-5

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Description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.Sulfamethoxazole N4-glucoside USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.Also, for use with USP monograph such as Sulfamethoxazole and Trimethoprim Oral Suspension

Application

Eribulin is a synthetic macrocyclic analog of halichondrin B that functions as a microtubule dynamics inhibitor, enabling suppression of mitotic spindle formation in rapidly dividing cells. It serves as a clinically validated antimitotic agent used in the treatment of metastatic breast cancer, offering a well-established mechanism of action through tubulin binding and inhibition of microtubule growth. Its structural complexity supports targeted cytotoxic activity with a defined pharmacological profile in oncology applications.

General Information

CAS No. 253128-41-5
Cat. No. CS-2802
Purity ≥98%
MDL No. MFCD23160037
Storage -80°C, protect from light
Shipping Shipping with dry ice.
Molecular Formula C₄₀H₅₉NO₁₁
Molecular Weight 729.90
Synonym(s) B1939; E7389; ER-086526
SMILES C=C1C[C@@](CC[C@@]2(C[C@@]3([H])O4)O[C@]([C@](O[C@](C5)([H])CC6)([H])[C@@]6([H])O7)([H])[C@@]4([H])[C@]7([H])[C@@]3([H])O2)([H])O[C@@]1([H])CC[C@](C[C@@H](C)C8=C)([H])O[C@]8([H])C[C@@](O[C@H](C[C@H](O)CN)[C@@H]9OC)([H])[C@]9([H])CC5=O

Computational Chemistry Data

TPSA 146.39
LogP 3.438
H_Acceptors 12
H_Donors 2
Rotatable_Bonds 4

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06,GHS08
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301+H311+H331-H341-H351-H361
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Alcohol

Building Blocks Functional Group Ether

Building Blocks Functional Group Ketone

Building Blocks Functional Group Olefins

Building Blocks Skeleton Bridge Rings compounds Other bridge ring compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science ADC Related Compound Payload

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Payload (Drug) Candidates

Biochemistry Biochemicals and Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Payload (Drug) Candidates

Biochemistry Pharmaceutical Development and Drug Discovery Research Antibody-Drug Conjugates (ADC) Preparation Research Reagents Payload (Drug) Candidates

Key Words

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Eribulin

CAS No. 253128-41-5

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