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Structure of 25354-42-1
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Cyclopropyl trifluoromethanesulfonate serves as a highly reactive triflate ester for cyclopropyl transfer in cross-coupling and functionalization reactions. The strained cyclopropyl ring enhances electrophilicity, while the trifluoromethylsulfonyl group ensures excellent leaving group ability. This combination enables efficient C–C bond formation under mild conditions.
Cyclopropyl trifluoromethanesulfonate serves as a highly reactive cyclopropyl transfer agent in transition-metal-catalyzed cross-coupling reactions. Its triflate leaving group enables efficient C–C bond formation under mild conditions, facilitating the direct introduction of cyclopropyl motifs into complex molecular architectures. The stability of the cyclopropyl ring and the robustness of the triflate functionality make this reagent particularly valuable for constructing bioactive scaffolds and natural product analogs with high functional group tolerance and predictable stereochemical outcomes.
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GHS No : GHS02,GHS05,GHS07
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Signal Word : Danger
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UN#: 2924
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Class : 3,8
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Packing Group : Ⅲ
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Hazard Statements : H225-H302-H314
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: