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CS-W001157 4
Total: USD 88.00

16-Bromohexadecanoic acid

  • CAS No. 2536-35-8

  • Cat. No. CS-0091012
  • Purity≥95%
  • MDL No.MFCD00040779

*For research and further manufacturing use only, not for direct human use.

16-Bromohexadecanoic acid|CS-0091012

Structure of 2536-35-8

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General Information

  • CAS No. 2536-35-8
  • Cat. No. CS-0091012
  • Purity ≥95%
  • MDL No. MFCD00040779
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₃₁BrO₂
  • Molecular Weight 335.33
  • Synonym(s) None
  • SMILES O=C(O)CCCCCCCCCCCCCCCBr

Application

16-Bromohexadecanoic acid serves as a versatile long-chain alkyl bromide building block for the synthesis of functionalized fatty acid derivatives and lipid analogs. Its terminal bromide enables efficient SN2 substitutions, facilitating the installation of diverse terminal functionalities. The carboxylic acid group provides a handle for amide coupling or esterification, supporting applications in bioconjugation and surfactant chemistry. The molecule exhibits good bench stability and is readily purified by recrystallization or chromatography, making it well-suited for routine synthetic workflows.

Synthesis

  • Route1

    References

    • Ohlsson, Joergen; Magnusson, Goeran Tetrahedron, 2000 , vol. 56, # 51 p. 9975 - 9984
  • Route2
    • null|null
      85115-82-8
    • ~67%
    • In-stock
      16-Bromohexadecanoic acid|CS-0091012
      2536-35-8

    References

    • Kimura, Yoshikazu; Regen, Steven L. Journal of Organic Chemistry, 1983 , vol. 48, # 9 p. 1533 - 1534
  • Route3
    • 16-Hexadecanolide|CS-0068061
      109-29-5
    • ~80%
    • In-stock
      16-Bromohexadecanoic acid|CS-0091012
      2536-35-8

    References

    • Fisher, Gregory L.; Walker, Amy V.; Hooper, Andrew E.; Tighe, Timothy B.; Bahnck, Kevin B.; Skriba, Hope T.; Reinard, Michael D.; Haynie, Brendan C.; Opila, Robert L.; Winograd, Nicholas; Allara, David L. Journal of the American Chemical Society, 2002 , vol. 124, # 19 p. 5528 - 5541

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   5.9273
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   15

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