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Structure of 2557-78-0
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2-Fluorothiophenol delivers a fluorinated thiophene scaffold with enhanced reactivity at the thiol site. The ortho-fluoro substitution imparts electronic modulation and improved metabolic stability, making it valuable for bioconjugation and synthetic intermediates in medicinal chemistry.
2-Fluorothiophenol serves as a versatile building block in synthetic organic chemistry, enabling the introduction of fluorinated thiophene motifs into complex molecules. Its reactive thiol group facilitates conjugate additions, metal-catalyzed couplings, and thioether formation under mild conditions. The ortho-fluorine substituent enhances metabolic stability and modulates electronic properties, making it valuable for medicinal chemistry and agrochemical scaffold development. Bench-stable and compatible with standard purification methods, it functions reliably in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H315-H319-H335
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Precautionary Statements : P210-P302+P352
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Lot numbers can be found on the outside label of a product: