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CS-W001157 4
Total: USD 88.00

m-PEG16-NHS ester

  • CAS No. 2563873-83-4

  • Cat. No. CS-0900853
  • Purity≥97%
  • MDL No.MFCD13184971
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

m-PEG16-NHS ester|CS-0900853

Structure of 2563873-83-4

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Description

This polyether-functionalized dioxopyrrolidinyl ester features a 47-atom aliphatic chain terminated by a reactive ester group, enabling efficient coupling to carboxylic acid-containing biomolecules. The extended polyether backbone imparts high solubility in polar solvents and enhances stability under aqueous conditions, making it suitable for conjugation workflows requiring prolonged shelf life and minimal aggregation.

Application

2,5-Dioxopyrrolidin-1-yl 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-hexadecaoxapentacontan-50-oate serves as a robust, bench-stable ester activating agent for carboxylic acids in peptide coupling and polymer functionalization. Its extended polyether chain enhances solubility in polar aprotic solvents while maintaining high reactivity under standard conditions. The N-hydroxypyrrolidone leaving group facilitates clean reaction progress with minimal racemization, enabling efficient formation of esters and amides across diverse substrates.

General Information

  • CAS No. 2563873-83-4
  • Cat. No. CS-0900853
  • Purity ≥97%
  • MDL No. MFCD13184971
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₈H₇₁NO₂₀
  • Molecular Weight 861.97
  • Synonym(s) None
  • SMILES O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)ON1C(CCC1=O)=O

Computational Chemistry Data

  • TPSA   211.36
  • LogP   -0.1209
  • H_Acceptors   20
  • H_Donors   0
  • Rotatable_Bonds   49

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

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