Methyl 4-amino-2-chloro-5-iodobenzoate

Name: Methyl 4-amino-2-chloro-5-iodobenzoate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 256935-85-0
Cat. No. CS-M3489
Purity≥98%
MDL No.MFCD09260863

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 4-amino-2-chloro-5-iodobenzoate|CS-M3489

Structure of 256935-85-0

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Methyl 4-amino-2-chloro-5-iodobenzoate features a trifunctional aromatic core with orthogonal reactivity, enabling selective coupling in late-stage diversification. The electron-donating amino group enhances nucleophilicity at C4, while the chloro and iodo substituents provide complementary handles for palladium-catalyzed cross-coupling. This combination delivers precise control over molecular architecture in synthetic sequences.

Application

Methyl 4-amino-2-chloro-5-iodobenzoate serves as a versatile building block for the synthesis of functionalized aromatic scaffolds. The molecule combines ortho-halogen (Cl, I) and amino functionalities, enabling sequential cross-coupling reactions such as Suzuki-Miyaura or Buchwald-Hartwig transformations. Its methyl ester group provides a handle for further derivatization, while the amino moiety offers nucleophilic reactivity. Bench-stable and readily purified by crystallization, it facilitates efficient access to complex heterocyclic systems and medicinally relevant frameworks in medicinal chemistry and process development.

General Information

CAS No. 256935-85-0
Cat. No. CS-M3489
Purity ≥98%
MDL No. MFCD09260863
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇ClINO₂
Molecular Weight 311.50
Synonym(s) Phenol,7-(bromomethyl)-,acetate
SMILES O=C(OC)C1=CC(I)=C(N)C=C1Cl

Computational Chemistry Data

TPSA 52.32
LogP 2.3134
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Iodide

Building Blocks Functional Group Chloride

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

Methyl 4-amino-2-chloro-5-iodobenzoate sigmaMethyl 4-amino-2-chloro-5-iodobenzoate manufacturerMethyl 4-amino-2-chloro-5-iodobenzoate priceMethyl 4-amino-2-chloro-5-iodobenzoate structureMethyl 4-amino-2-chloro-5-iodobenzoate SDSbuy Methyl 4-amino-2-chloro-5-iodobenzoateMethyl 4-amino-2-chloro-5-iodobenzoate supplierMethyl 4-amino-2-chloro-5-iodobenzoate usesMethyl 4-amino-2-chloro-5-iodobenzoate molecular weightprice of Methyl 4-amino-2-chloro-5-iodobenzoateMethyl 4-amino-2-chloro-5-iodobenzoate chemical name formula of Methyl 4-amino-2-chloro-5-iodobenzoate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 4-amino-2-chloro-5-iodobenzoate

CAS No. 256935-85-0

Recommended Products