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Structure of 256935-86-1
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6-Chloro-1H-indole-5-carboxylic acid integrates a chlorine substituent at the 6-position and a carboxylic acid group at the 5-position of the indole core. This configuration imparts enhanced electronic effects and solubility, enabling efficient coupling in synthetic routes for pharmaceutical intermediates and bioactive heterocycles.
6-Chloro-1H-indole-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized indole scaffolds. Its carboxylic acid group facilitates direct coupling reactions and derivatization, while the chloro substituent provides a handle for subsequent cross-coupling or nucleophilic substitution. The compound exhibits good bench stability and is compatible with standard synthetic protocols, making it well-suited for the construction of complex heterocyclic systems and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: