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Structure of 925179-02-8
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This difluoromethyl-substituted pyrazole carboxylic acid features a strategically positioned electron-deficient fluorinated moiety that enhances metabolic stability and modulates lipophilicity. The rigid, planar heterocyclic core facilitates integration into bioactive scaffolds, while the carboxylic acid group enables direct conjugation or salt formation for improved solubility in medicinal chemistry applications.
1-(Difluoromethyl)-1H-pyrazole-3-carboxylic acid serves as a versatile building block for bioactive heterocycles, enabling efficient access to fluorinated pharmaceutical scaffolds. Its difluoromethyl group enhances metabolic stability and modulates lipophilicity, while the pyrazole-carboxylic acid core facilitates coupling reactions and hydrogen bonding in medicinal chemistry applications. The compound exhibits good bench stability and is amenable to standard purification techniques, supporting reliable integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P264-P270-P330
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Lot numbers can be found on the outside label of a product: