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Structure of 2591-86-8
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Bromoacetamido-PEG8-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Piperidine-1-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient synthesis of nitrogen-containing heterocycles and bioactive molecules. Its aldehyde functionality facilitates reductive amination, imine formation, and coupling reactions with amines, hydrazines, and nucleophiles under mild conditions. The molecule exhibits good bench stability and is readily purified by distillation or chromatography, making it suitable for scale-up and multi-step synthetic sequences.
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H311-H319
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P361+P364-P405-P501
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Lot numbers can be found on the outside label of a product: