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Structure of 259209-24-0
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This boronic acid features a fluorinated aryl ring paired with a hydroxyl group, enabling selective coupling in Suzuki-Miyaura reactions. The ortho-hydroxy functionality enhances stability and directs regiochemistry during palladium-catalyzed transformations.
(3-Fluoro-2-hydroxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The ortho-hydroxyl group enhances regioselectivity and facilitates chelation-assisted coupling, while the fluorine substituent provides metabolic stability and modulates electronic properties. Bench-stable and readily purified by recrystallization, it exhibits good functional group tolerance, making it ideal for late-stage diversification in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P233-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: