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Structure of 26018-66-6
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6-Fluorobenzofuran-2-carboxylic acid features a fluorinated benzofuran scaffold with a carboxylic acid at the 2-position, offering enhanced electronic modulation and metabolic stability. This structural motif enables direct incorporation into bioactive molecules for medicinal chemistry campaigns targeting CNS disorders and kinase inhibition.
6-Fluorobenzofuran-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation of fluorinated benzofuran scaffolds into bioactive molecules. Its carboxylic acid functionality facilitates amide bond formation, esterification, and metal-catalyzed coupling reactions. The fluorine substituent enhances metabolic stability and modulates electronic properties, while the rigid benzofuran core provides structural preorganization for target binding. This compound exhibits excellent bench stability and compatibility with standard purification methods, supporting its use in both small-scale synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: