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CS-W001157 4
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10H-Benzo[b]pyrido[2,3-e][1,4]thiazine

  • CAS No. 261-96-1

  • Cat. No. CS-W015605
  • Molecule weight200.26
  • Purity≥95%
  • MDL No.MFCD00160449

*For research and further manufacturing use only, not for direct human use.

10H-Benzo[b]pyrido[2,3-e][1,4]thiazine|CS-W015605

Structure of 261-96-1

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General Information

  • CAS No. 261-96-1
  • Cat. No. CS-W015605
  • Purity ≥95%
  • MDL No. MFCD00160449
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₈N₂S
  • Molecular Weight 200.26
  • Synonym(s) 10H-Pyrido[3,2-b][1,4]benzothiazine
  • SMILES C12=CC=CC=C1NC3=NC=CC=C3S2

Description

10H-Benzo[b]pyrido[2,3-e][1,4]thiazine is a polycyclic heteroaromatic compound featuring a fused benzothiazine core with extended π-conjugation. This rigid, planar structure exhibits enhanced stability and electron-rich character, enabling effective integration into organic semiconductors and fluorescent probes. The molecule's defined electronic profile supports applications in photoluminescent materials and advanced synthetic intermediates.

Application

10H-Benzo[b]pyrido[2,3-e][1,4]thiazine serves as a versatile heterocyclic scaffold in medicinal chemistry, enabling the construction of diverse fused ring systems through standard electrophilic and transition-metal-catalyzed transformations. Its inherent bench stability and defined aromaticity facilitate straightforward functionalization at multiple sites, supporting efficient synthesis of complex molecular architectures relevant to targeted therapeutic discovery.

Synthesis

  • Route1

    References

    • Atkinson; Russ; Tucker Journal of medicinal chemistry, 1971 , vol. 14, # 10 p. 1005 - 1007
  • Route2

    References

    • Beresneva; Abele Chemistry of Heterocyclic Compounds, 2012 , vol. 48, # 9 p. 1420 - 1422 Khim. Geterotsikl. Soedin., 2012 , vol. 48, # 9 p. 1521 - 1524,3
  • Route3
    • null|null
      504-29-0
    • ~%
    • In-stock
      10H-Benzo[b]pyrido[2,3-e][1,4]thiazine|CS-W015605
      261-96-1

    References

    • Madrid, Peter B.; Polgar, Willma E.; Toll, Lawrence; Tanga, Mary J. Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 11 p. 3014 - 3017

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   24.92
  • LogP   3.2898
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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