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Structure of 273-05-2
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3H-[1,2,3]Triazolo[4,5-c]pyridine is a nitrogen-rich heterocycle featuring a fused triazole and pyridine core, offering high electron density and enhanced stability. This scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry and materials science due to its planar geometry and favorable binding interactions.
3H-[1,2,3]Triazolo[4,5-c]pyridine serves as a versatile heterocyclic scaffold in medicinal chemistry, enabling efficient construction of bioactive molecules through its reactive nitrogen sites. The core structure exhibits robust bench stability and compatibility with common functional groups, facilitating direct derivatization via electrophilic substitution or transition-metal-catalyzed coupling. Its rigidity and planarity support target-directed design in kinase inhibitors and CNS-active compounds, while the triazole-pyridine fusion enhances metabolic stability and solubility profiles in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: