2,5-Difluorobenzene-1-sulfonyl chloride

Name: 2,5-Difluorobenzene-1-sulfonyl chloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 26120-86-5
Cat. No. CS-W010484
Purity≥97%
MDL No.MFCD00060682

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,5-Difluorobenzene-1-sulfonyl chloride|CS-W010484

Structure of 26120-86-5

Size

Price

Quantity

* Please select Quantity before adding items.

Description

2,5-Difluorobenzene-1-sulfonyl chloride features a fluorinated aromatic ring with strategically positioned sulfonyl chloride functionality. This electrophilic reagent enables direct sulfonation of nucleophiles under mild conditions, offering high chemoselectivity in complex reaction environments. The electron-withdrawing fluorine substituents enhance reactivity while maintaining stability during storage and handling.

Application

2,5-Difluorobenzene-1-sulfonyl chloride serves as a versatile sulfonylating agent for the introduction of a difluorinated benzenesulfonyl group into target molecules. Its reactivity enables efficient formation of sulfonamide and sulfonate derivatives under mild conditions, with good bench stability and ease of purification. The ortho-fluorine substituents enhance electrophilicity and provide useful handles for downstream functionalization, making it valuable in medicinal chemistry and API scaffold construction.

General Information

CAS No. 26120-86-5
Cat. No. CS-W010484
Purity ≥97%
MDL No. MFCD00060682
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₃ClF₂O₂S
Molecular Weight 212.60
Synonym(s) 2,5-Difluorobenzenesulfonyl chloride
SMILES O=S(C1=CC(F)=CC=C1F)(Cl)=O

Computational Chemistry Data

TPSA 34.14
LogP 1.8923
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 3265
Class : 8	Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Sulfonyl Chloride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2,5-Difluorobenzene-1-sulfonyl chloride sigma2,5-Difluorobenzene-1-sulfonyl chloride manufacturer2,5-Difluorobenzene-1-sulfonyl chloride price2,5-Difluorobenzene-1-sulfonyl chloride structure2,5-Difluorobenzene-1-sulfonyl chloride SDSbuy 2,5-Difluorobenzene-1-sulfonyl chloride2,5-Difluorobenzene-1-sulfonyl chloride supplier2,5-Difluorobenzene-1-sulfonyl chloride uses2,5-Difluorobenzene-1-sulfonyl chloride molecular weightprice of 2,5-Difluorobenzene-1-sulfonyl chloride2,5-Difluorobenzene-1-sulfonyl chloride chemical name formula of 2,5-Difluorobenzene-1-sulfonyl chloride

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2,5-Difluorobenzene-1-sulfonyl chloride

CAS No. 26120-86-5

Recommended Products