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Structure of 367-30-6
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2,5-Difluoroaniline was used in the synthesis of 2,4-di-tert-butyl-6-[(2,5-difluorophenyl)iminomethyl]phenol. It was also used in ultrasound-assisted preparation of 1,4-diazabutadienes.
2,5-Difluoroaniline serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering enhanced metabolic stability and modulated electronic properties through its ortho-fluorine substituents. The amine functionality enables straightforward derivatization via amide coupling, reductive amination, or electrophilic substitution, while the difluoro pattern supports predictable regioselectivity in subsequent functionalizations. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for multi-step synthetic sequences and scale-up applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: