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Structure of 26429-41-4
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1,2-Dibromo-3-nitrobenzene features a nitro group flanked by two bromine substituents on adjacent carbons, creating a highly electron-deficient aromatic core. This configuration enables direct functionalization in cross-coupling reactions and facilitates selective substitution under mild conditions. The molecule exhibits enhanced stability during handling and integrates efficiently into complex synthetic sequences requiring precise regiocontrol.
1,2-Dibromo-3-nitrobenzene serves as a versatile dihalogenated building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of substituted biaryl and heteroaryl scaffolds. The nitro group enhances electrophilicity at the ortho position, facilitating directed functionalization, while the bromine atoms offer orthogonal reactivity in sequential coupling processes. Bench-stable and readily purified by column chromatography, it functions reliably in standard synthetic workflows requiring selective C–C bond formation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: