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Structure of 26557-78-8
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4-(2-Propynyloxy)aniline features a propargylic ether linkage appended to an aniline scaffold, enabling efficient coupling in transition-metal-catalyzed reactions. The terminal alkyne group supports click chemistry applications, while the aromatic amine offers tunable basicity and π-conjugation. This bifunctional architecture facilitates modular synthesis of complex architectures under mild conditions.
4-(2-Propynyloxy)aniline serves as a versatile building block for the synthesis of functionalized anilines and heterocyclic scaffolds. The propargyloxy group enables facile copper-catalyzed azide-alkyne cycloaddition (CuAAC), facilitating the construction of triazoles under mild conditions. Its stability, compatibility with common protecting groups, and ease of purification make it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: