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CS-W001157 4
Total: USD 88.00

Ethyl 2,2-difluoro-2-(pyridin-2-yl)acetate

  • CAS No. 267876-28-8

  • Cat. No. CS-0001531
  • Purity≥97%
  • MDL No.MFCD06858718

*For research and further manufacturing use only, not for direct human use.

Ethyl 2,2-difluoro-2-(pyridin-2-yl)acetate|CS-0001531

Structure of 267876-28-8

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General Information

  • CAS No. 267876-28-8
  • Cat. No. CS-0001531
  • Purity ≥97%
  • MDL No. MFCD06858718
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉F₂NO₂
  • Molecular Weight 201.17
  • Synonym(s) Ethyl Difluoro(pyridin-2-yl)acetate
  • SMILES FC(C1=NC=CC=C1)(F)C(OCC)=O

Synthesis

  • Route1
    • null|null
      109-04-6
    • null|null
      667-27-6
    • ~81%
    • Ethyl 2,2-difluoro-2-(pyridin-2-yl)acetate|CS-0001531
      267876-28-8

    References

    • Ashwood, Michael S.; Alabaster, Ramon J.; Cottrell, Ian F.; Cowden, Cameron J.; Davies, Antony J.; Dolling, Ulf H.; Emerson, Khateeta M.; Gibb, Andrew D.; Hands, David; Wallace, Debra J.; Wilson, Robert D. Organic Process Research and Development, 2004 , vol. 8, # 2 p. 192 - 200
  • Route2
    • null|null
      38078-09-0
    • Ethyl 2-oxo-2-(pyridin-2-yl)acetate|CS-0049502
      55104-63-7
    • ~%
    • Ethyl 2,2-difluoro-2-(pyridin-2-yl)acetate|CS-0001531
      267876-28-8

    References

    • Merck and Co., Inc. Patent: US6455532 B1, 2002 ; US 6455532 B1
  • Route3
    • Ethyl 2-oxo-2-(pyridin-2-yl)acetate|CS-0049502
      55104-63-7
    • ~77%
    • Ethyl 2,2-difluoro-2-(pyridin-2-yl)acetate|CS-0001531
      267876-28-8

    References

    • Ashwood, Michael S.; Alabaster, Ramon J.; Cottrell, Ian F.; Cowden, Cameron J.; Davies, Antony J.; Dolling, Ulf H.; Emerson, Khateeta M.; Gibb, Andrew D.; Hands, David; Wallace, Debra J.; Wilson, Robert D. Organic Process Research and Development, 2004 , vol. 8, # 2 p. 192 - 200

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   1.7365
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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