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Structure of 27034-51-1
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Ethyl 6-chloroindole-2-carboxylate features a chlorinated indole core with a carboxylate ester at the C2 position, enabling direct integration into heterocyclic scaffolds. The electron-deficient indole ring enhances reactivity in transition-metal-catalyzed couplings, while the ethyl ester facilitates downstream functionalization. This bench-stable derivative serves as a key intermediate in medicinal chemistry and materials synthesis.
Ethyl 6-chloroindole-2-carboxylate serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C6 position of the indole scaffold. Its chloro group facilitates palladium-catalyzed cross-coupling reactions, while the ester functionality supports selective reduction or hydrolysis to access carboxylic acid derivatives. The compound exhibits good bench stability and compatibility with standard synthetic workflows, making it well-suited for the construction of complex heterocyclic architectures and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: