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Structure of 272-52-6
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1H-Pyrazolo[4,3-b]pyridine is a nitrogen-rich heterocycle featuring fused pyrazole and pyridine rings, offering enhanced planarity and electron-deficient character. This scaffold integrates readily into bioactive molecules, enabling strong π-stacking interactions and improved metabolic stability in pharmaceutical applications.
1H-Pyrazolo[4,3-b]pyridine serves as a privileged heterocyclic scaffold in medicinal chemistry, enabling efficient access to bioactive molecules through its inherent planarity and hydrogen-bonding capacity. The core structure exhibits robust bench stability and compatibility with common coupling reactions, facilitating functionalization at multiple positions. Its utility spans catalytic transformations and modular synthesis of kinase inhibitors, GPCR modulators, and other pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: