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Structure of 27245-31-4
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This piperazinylpropanoic acid derivative features a flexible aliphatic chain linking a protonatable piperazine ring to a carboxylic acid group. The molecule integrates a basic nitrogen-rich pharmacophore with a polar, ionizable terminus, enabling strong hydrogen bonding and enhanced solubility in aqueous media. Its structure supports efficient conjugation and salt formation for improved bioavailability.
3-(Piperazin-1-yl)propanoic acid serves as a versatile bifunctional building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptide conjugates. The piperazine moiety provides enhanced solubility and hydrogen-bonding capacity, while the carboxylic acid facilitates amide coupling and derivatization under standard conditions. Its bench-stable nature and compatibility with diverse reaction environments make it a practical choice for scaffold diversification in drug discovery workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: