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CS-W001157 4
Total: USD 88.00

3-(Piperazin-1-yl)propanoic acid

  • CAS No. 27245-31-4

  • Cat. No. CS-0266536
  • Purity≥95%
  • MDL No.MFCD03161179
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-(Piperazin-1-yl)propanoic acid|CS-0266536

Structure of 27245-31-4

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Description

This piperazinylpropanoic acid derivative features a flexible aliphatic chain linking a protonatable piperazine ring to a carboxylic acid group. The molecule integrates a basic nitrogen-rich pharmacophore with a polar, ionizable terminus, enabling strong hydrogen bonding and enhanced solubility in aqueous media. Its structure supports efficient conjugation and salt formation for improved bioavailability.

Application

3-(Piperazin-1-yl)propanoic acid serves as a versatile bifunctional building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptide conjugates. The piperazine moiety provides enhanced solubility and hydrogen-bonding capacity, while the carboxylic acid facilitates amide coupling and derivatization under standard conditions. Its bench-stable nature and compatibility with diverse reaction environments make it a practical choice for scaffold diversification in drug discovery workflows.

General Information

  • CAS No. 27245-31-4
  • Cat. No. CS-0266536
  • Purity ≥95%
  • MDL No. MFCD03161179
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄N₂O₂
  • Molecular Weight 158.20
  • Synonym(s) None
  • SMILES O=C(O)CCN1CCNCC1

Computational Chemistry Data

  • TPSA   52.57
  • LogP   -0.6337
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group :
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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