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Structure of 273384-78-4
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1-(2-Trifluoromethylphenyl)ethylamine is a bench-stable, moisture-tolerant amine featuring a sterically hindered ethyl spacer linking the aromatic ring to the nitrogen. The para-trifluoromethyl group imparts strong electron-withdrawing character, enhancing reactivity in coupling processes. This structure enables efficient incorporation into bioactive scaffolds and functional polymers.
1-(2-Trifluoromethylphenyl)ethylamine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its trifluoromethyl group enhances metabolic stability and modulates lipophilicity, while the benzylic amine functionality facilitates straightforward derivatization via alkylation, acylation, or reductive amination. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for scalable synthesis and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: