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CS-W001157 4
Total: USD 88.00

5-(Methylamino)pentan-1-ol

  • CAS No. 2751-70-4

  • Cat. No. CS-0570792
  • Molecule weight117.19
  • Purity≥97%
  • MDL No.MFCD16696454

*For research and further manufacturing use only, not for direct human use.

5-(Methylamino)pentan-1-ol|CS-0570792

Structure of 2751-70-4

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General Information

  • CAS No. 2751-70-4
  • Cat. No. CS-0570792
  • Purity ≥97%
  • MDL No. MFCD16696454
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₅NO
  • Molecular Weight 117.19
  • Synonym(s) None
  • SMILES OCCCCCNC

Description

5-(Methylamino)pentan-1-ol features a primary alcohol terminal group paired with a pendant methylamino substituent, enabling dual functionalization in synthetic sequences. This bifunctional scaffold supports efficient conjugation and coupling reactions under standard conditions, offering enhanced solubility and stability in aqueous and organic media.

Application

5-(Methylamino)pentan-1-ol serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient synthesis of amino-alcohol scaffolds. The primary alcohol facilitates derivatization via esterification, etherification, or oxidation to carboxylic acid, while the pendant methylamino group supports salt formation and hydrogen bonding interactions. Its stability under standard reaction conditions and compatibility with common protecting group strategies make it well-suited for iterative synthetic sequences and library generation.

Synthesis

  • Route1
    • null|null
      95732-46-0
    • ~81%
    • In-stock
      5-(Methylamino)pentan-1-ol|CS-0570792
      2751-70-4

    References

    • Sankyo Company, Limited Patent: EP1746095 A1, 2007 ; Location in patent: Page/Page column 82 ;
  • Route2
    • In-stock
      5-Chloropentan-1-ol|CS-0095410
      5259-98-3
    • null|null
      74-89-5
    • ~63%
    • In-stock
      5-(Methylamino)pentan-1-ol|CS-0570792
      2751-70-4

    References

    • CNRS Patent: US6972343 B1, 2005 ; Location in patent: Page/Page column 24 ;
  • Route3
    • null|null
      2622-48-2
    • ~%
    • In-stock
      5-(Methylamino)pentan-1-ol|CS-0570792
      2751-70-4

    References

    • Glacet,C.; Veron,D. Bulletin de la Societe Chimique de France, 1965 , p. 1789 - 1794

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅱ
Hazard Statements : H227-H302-H314-H333
Precautionary Statements : P210-P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P370+P378-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   0.3684
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   5

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