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Structure of 2757082-72-5
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This chiral oxazole features a tert-butyl group and a pyrimidin-2-yl substituent, offering enhanced steric bulk and electronic modulation. The dihydrooxazole core provides a rigid, electron-deficient scaffold ideal for coupling reactions and structural integration in medicinal chemistry. Bench-stable under standard conditions, it enables efficient access to complex heterocyclic architectures with controlled stereochemistry.
(R)-4-(tert-Butyl)-2-(pyrimidin-2-yl)-4,5-dihydrooxazole serves as a stable, bench-ready heterocyclic building block for medicinal chemistry. Its dihydrooxazole core enables selective transformations in late-stage functionalization, while the tert-butyl group enhances solubility and reduces aggregation during synthesis. The pyrimidinyl moiety provides a versatile handle for cross-coupling and further derivatization, making it well-suited for constructing complex API-relevant scaffolds with predictable reactivity and high functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: