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CS-W001157 4
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Isophthalic dihydrazide

  • CAS No. 2760-98-7

  • Cat. No. CS-0149903
  • Purity≥98%
  • MDL No.MFCD00025117

*For research and further manufacturing use only, not for direct human use.

Isophthalic dihydrazide|CS-0149903

Structure of 2760-98-7

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General Information

  • CAS No. 2760-98-7
  • Cat. No. CS-0149903
  • Purity ≥98%
  • MDL No. MFCD00025117
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₄O₂
  • Molecular Weight 194.19
  • Synonym(s) Isophthalohydrazide; Isophthalic dihydrazide
  • SMILES NNC(C1=CC=CC(C(NN)=O)=C1)=O

Description

Isophthalic dihydrazide features two hydrazide functional groups flanked by a rigid para-substituted benzene ring, enabling robust coordination in metal-organic frameworks and efficient coupling in peptide synthesis. This bench-stable, moisture-tolerant reagent integrates seamlessly into polymer backbones and bioconjugation workflows under standard conditions.

Application

Isophthalic dihydrazide serves as a versatile building block in the synthesis of polyamides, heterocycles, and coordination polymers. Its two hydrazide groups enable efficient condensation reactions with aldehydes, ketones, and carboxylic acid derivatives under mild conditions. The meta-substituted aromatic core provides structural rigidity and enhanced thermal stability, making it suitable for high-performance materials. Bench-stable and readily purified by recrystallization, it functions reliably in both laboratory-scale syntheses and scalable industrial processes.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   110.24
  • LogP   -1.1064
  • H_Acceptors   4
  • H_Donors   4
  • Rotatable_Bonds   2

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