4-Bromo-5-fluoro-3-iodopyridin-2-amine

Name: 4-Bromo-5-fluoro-3-iodopyridin-2-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 2762907-70-8
Cat. No. CS-0885622
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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4-Bromo-5-fluoro-3-iodopyridin-2-amine|CS-0885622

Structure of 2762907-70-8

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Description

4-Bromo-5-fluoro-3-iodopyridin-2-amine features a tri-substituted pyridine core with orthogonal halogen handles enabling sequential cross-coupling. The electron-deficient ring facilitates palladium-catalyzed transformations, while the amine group serves as a direct coupling partner. This molecule integrates readily into complex heterocyclic scaffolds under standard conditions.

Application

4-Bromo-5-fluoro-3-iodopyridin-2-amine serves as a versatile building block for the synthesis of functionalized pyridine derivatives. Its orthogonal halogenation pattern enables sequential cross-coupling reactions, facilitating the construction of complex heterocyclic scaffolds. The compound exhibits good bench stability and is compatible with palladium-catalyzed coupling protocols, making it well-suited for medicinal chemistry and process development workflows.

General Information

CAS No. 2762907-70-8
Cat. No. CS-0885622
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₃BrFIN₂
Molecular Weight 316.90
Synonym(s) None
SMILES NC1=NC=C(F)C(Br)=C1I

Computational Chemistry Data

TPSA 38.91
LogP 2.17
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Other Classifications

Building Blocks Functional Group Iodide

Building Blocks Functional Group Fluoride

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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4-Bromo-5-fluoro-3-iodopyridin-2-amine

CAS No. 2762907-70-8

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