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Structure of 27655-41-0
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5-Isoquinolinecarbonitrile is a bench-stable, electron-deficient heteroaromatic scaffold featuring a nitrile group at the 5-position of the isoquinoline core. This configuration enables direct incorporation into C–C and C–heteroatom coupling reactions, serving as a versatile building block for pharmaceutical intermediates and functional materials.
5-Isoquinolinecarbonitrile serves as a versatile building block in medicinal chemistry, enabling efficient construction of isoquinoline-based scaffolds through palladium-catalyzed couplings and nucleophilic addition reactions. Its nitrile group provides a handle for selective transformations, including reduction to aldehyde or amine functionalities, while maintaining stability under standard synthetic conditions. The molecule exhibits excellent bench stability and compatibility with diverse functional groups, facilitating its use in multi-step synthesis and high-throughput screening campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: