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Structure of 27810-64-6
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Isoquinoline-5-carboxylic acid features a rigid heteroaromatic core with a carboxylic acid group at the 5-position, enabling direct conjugation in bioactive molecule design. This configuration supports hydrogen bonding and dipole interactions in target binding sites. The compound exhibits enhanced solubility in polar solvents compared to unsubstituted analogs and maintains stability under standard bench conditions.
Isoquinoline-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its carboxylic acid group facilitates amide bond formation and derivatization, while the isoquinoline core provides a rigid, aromatic scaffold with favorable pharmacokinetic properties. The compound exhibits good bench stability and is compatible with common purification methods, making it well-suited for iterative synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P264-P270-P280-P301+P310-P305+P351+P338-P330-P337+P313-P501
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Lot numbers can be found on the outside label of a product: