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Structure of 276861-63-3
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This trifluoromethyl-substituted benzoic acid features a methoxy group at the ortho position, delivering enhanced solubility and metabolic stability. The electron-withdrawing trifluoromethyl moiety imparts strong acidity and polar character, enabling efficient coupling in amide bond formation. Ideal for pharmaceutical intermediates and bioactive molecule synthesis under standard conditions.
3-Methoxy-4-(trifluoromethyl)benzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, offering enhanced lipophilicity and metabolic stability through its trifluoromethyl group. The carboxylic acid functionality enables straightforward derivatization into amides, esters, and acyl chlorides, while the methoxy substituent provides predictable electronic modulation. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthesis workflows and scale-up applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: