(S)-1-(Pyridin-4-yl)ethan-1-amine

Name: (S)-1-(Pyridin-4-yl)ethan-1-amine
Brand: ChemScene
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CAS No. 27854-96-2
Cat. No. CS-0098146
Purity≥97%
MDL No.MFCD09256819

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(S)-1-(Pyridin-4-yl)ethan-1-amine|CS-0098146

Structure of 27854-96-2

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Description

(S)-1-(Pyridin-4-yl)ethan-1-amine features a chiral center adjacent to a pyridine ring, delivering high enantioselectivity in asymmetric synthesis. This bench-stable amine integrates readily into catalytic systems and ligand architectures, offering enhanced stereocontrol through its well-defined spatial orientation and nitrogen basicity.

Application

(S)-1-(Pyridin-4-yl)ethan-1-amine serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its pyridyl group facilitates transition-metal-catalyzed couplings, while the chiral amine center supports stereoselective transformations. The compound exhibits good bench stability, ease of purification, and compatibility with common protecting group strategies, making it well-suited for iterative synthesis workflows.

General Information

CAS No. 27854-96-2
Cat. No. CS-0098146
Purity ≥97%
MDL No. MFCD09256819
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₀N₂
Molecular Weight None
Synonym(s) methyl-pyridin-4-ylmethyl-amine
SMILES N[C@@H](C)C1=CC=NC=C1

Computational Chemistry Data

TPSA 38.91
LogP 1.1013
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS05,GHS06
Signal Word : Danger	UN#: 2922
Class : 8(6.1)	Packing Group : Ⅲ
Hazard Statements : H301-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-1-(Pyridin-4-yl)ethan-1-amine

CAS No. 27854-96-2

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